Separarea izomerilor de metamfetamină prin acid tartric

[Osmosis Vanderwaal]

@G.Patton Am câteva probleme cu acest proces pe care sper că mi le puteți explica.
Nu se menționează D-meth-D-tartatul sau l-meth-l-tartatul. Aceștia sunt stereoisomerii optic activi și nu am văzut nicio dovadă sau mecanism care să sugereze că aceștia nu se formează. Fiind stereoizomerii optic activi, aceștia ar cristaliza la o temperatură mai ridicată ( adică mai devreme) decât cei inactivi. Ordinea ar fi: D,D; L,L; D,L; L,D.
De ce NU ar fi mai rentabil și mai eficient să se utilizeze DOAR acid l-tartric, izomerii naturali, și să se elimine cristalele de ,l l-meth din rm înainte de concentrare și cristalizare?

 

[G.Patton]

Acest lucru se datorează obstacolelor spațiale. Ele nu pot fi formate. Acest lucru este descris în literatura de specialitate cu alte exemple de amine. Căutați-l dacă sunteți interesat.

Puteți, depinde de dvs. Rezultatul va fi același.

 

[EveryoneHatesCris]

Okay?

 

[Osmosis Vanderwaal]

@G.Patton I find it interesting that you are reacting ammonium chloride with sulfuric acid to make your HCL gas in this write up. I've never before heard of using that method but it is viable. Is there a reason that is preffered over the more common mixtures?

 

[G.Patton]

No difference, It's up you your local reagent availability.

 

[Osmosis Vanderwaal]

I like that there is no water to gunk up the works, like there is dehydrating HCL with H2So4. I think I'll adot this method andski the drying tube

 

[G.Patton]

It's easy to get rid of water by means of CaCl2 tube filter.

 

[Osmosis Vanderwaal]

sure, or a cold trap with H2So4 inline with the output, but if I skip that I can just have a flask, a claison adaptor with a pressure equalizing drop funnel and a hose adaptor on the side arm. 4 pieces of glass, only the drop funnel being extra from a basic distillation set

 

[prvnc]

The tartaric acid method works by selectively crystallizing d-methamphetamine as the l-tartrate salt. Control pH carefully during freebase conversion and HCl gas saturation. Hot filtration and recrystallization in ethanol boost purity but reduce yield (~30% loss normal). Always verify purity with Simon’s test. Exact tartaric acid ratios and repeat crystallizations improve results.

 

[Osmosis Vanderwaal]

theres a rule that says "a good chmist is an accurate chemist" Tartaric acid doesn't "selectively crystallise" anything. that misleading Also d-meth-l tartrate mixes more than one convention of chirality, considering
d-meth=L-Meth=R=meth=legal, and
l-meth=D-meth=S-meth=illegal