Is it possible to add hydrobromic acid to ethyl acetate without using acetone?

[Come on 666]

I synthesized 2-bromo-4'-methylpropiophenone according to the method in the video，

However, the synthesis of 4-MMC using 2-bromo-4'-methylpropiophenone failed.

And I don't know where the problem is,Is there anyone who has successfully synthesized 4-MMC? Please help me, we can discuss the synthesis of 4-MMC together.

 

[mephedrone_4-mmc]

4mpp to 2b4m.
Then 2b4m to 4mmc.


4mpp.
Hbr
H2o2

Your get 2b4m liquid

Liquid 2b4m.
EA.
MA 40%


WASH WITH 10% NAOH OR BAKING SODA with 1 TIMES.
Then cold water wash with 4 times.

THEN COOL IT SOLUTION -15DEGREE FOR 12 HOURS

IN SOLUTION ADD -15 DEGREE ACETONE.
STIRRER 10 TO 15 MIN.

5 KG SOLUTION 10 KG ACETONE
I USED WEIGHT MACHINE.

THEN START ADDING HBR FOR ACIDITY. Until PH 5.

After that OPEN THE LID AND blow air.

I USED DC FAN FOR BLOW ALL AIR AMD SOLUTION.


STIRRER AND BLOW AIR FOR ALL ACETONE DISAPPEARED.

ITS NORMALLY TAKES 12 HOURS.
IN THAT TIME SOME SAME PARTICAL form BUT ITS NOT CRYSTAL ITS ONLY POWDER.

Wash with acetone

WHAS IT HEAT WITH SOME SOLUTION THEN YOU GET CRYSTAL.

 

[Come on 666]

100 g 2-bromo-4'-methylpropiophenone，N-Methyl-2-pyrrolidone (NMP; cas 872-50-4) 400ML，Methylamine 40% aqueous solution (cas 74-89-5) 200 ml，Ethyl acetate 500 ml
What concentration of sodium bicarbonate in water should I use for cleaning?
How many milliliters of sodium bicarbonate solution should I use?

 

[mephedrone_4-mmc]

No. Where you read about magnesium sulfate.

 

[Come on 666]

Mephedrone synthesis (4-MMC) in NMP solvent. Large scale.

Reaction scheme: Reagents: 2-Bromo-4'-methylpropiophenone (cas 1451-82-7) - 5 kg; n-Methyl-2-pyrrolidone (NMP; cas 872-50-4) - 20 L; Methyl amine 40% aq. solution (cas 74-89-5) - 8 L; Benzene - 20 L; Acetone - 30 L; Hydrochloric acid con. aq. solution (HCl 36%) ~ 1.5 L; Distilled water - 20...

bbgate.com

4-MMC (mephedrone) synthesis. Bromination in dichlormethane.

We'll consider mephedrone (4MMC) synthesis in this article. Dichloromethane (DCM) is used as a solvent. It has a low boiling point (~40 °C) and synthesis procedures take a little time. Work conditions: Air temperature 20-24 ºC; Relative humidity

bbgate.com

Both articles say to use anhydrous magnesium sulfate for drying, but other videos and articles do not use anhydrous magnesium sulfate.

 

[Come on 666]

I bought hydrochloric acid. It will arrive in a few days, and I will do the next experiment, because I think hydrobromic acid is not very good. I want to use hydrochloric acid, and I will report the results to you when the time comes.

 

[mephedrone_4-mmc]

I used hydrobromic acid for acidification

 

[mephedrone_4-mmc]

What is your starting material?

2b4m or 4mpp

 

[Come on 666]

2-Bromo-4'-methylpropiophenone I have What is 4mpp?

 

[mephedrone_4-mmc]

4mpp = 4 methylpropiophenone