He estado buscando en el foro y hay muchas formas diferentes de producir mefedrona. ¿Cuál crees que es la síntesis que tiene un rendimiento realmente bueno, es bastante sencilla y tiene menos probabilidades de ser detectada?
¿Cuál es la mejor síntesis de Mefedrona (4-MMC)?
- Thread starter PabloEscobar
- Start date
Depende de los reactivos de partida. Buenas formas mediante 2-brormo o 2-yodo-4'-metilpropiofenona
¿podría decirme qué hacer si la 4metipropiofenona está regulada?
- By HIGGS BOSSON
En este caso, puede elegir las siguientes opciones:
1. Aclarar si el bromo (BK-4) o la yodocetona (IK-4) son legales y, en caso afirmativo, encargar la sustancia a China.
2. Sintetizar tú mismo 4-metilpropiofenona (la síntesis está en el foro).
3. Sustituya la 4-metilpropiofenona por la 3-cloropropiofenona u otro análogo.
1. Aclarar si el bromo (BK-4) o la yodocetona (IK-4) son legales y, en caso afirmativo, encargar la sustancia a China.
2. Sintetizar tú mismo 4-metilpropiofenona (la síntesis está en el foro).
3. Sustituya la 4-metilpropiofenona por la 3-cloropropiofenona u otro análogo.
2-Bromo-4'-methylpropiophenone (cas 1451-82-7) Making 4MMC，The simplest synthesis method?
It's not like there's too many options.
React 2b4m with methylamine. I prefer methylamine hydrochloride (easier to handle, less smell) but 40 % solution works just as well. Use whatever solvent you can get the easiest and without drawing attention, usually ethyl acetate but possibly DCM, toluene or benzene.
The process is the same: reaction, free base flushing, acidification, extraction, drying and/or recrystallization.
Consider performing acidification in aqueous environment without acetone. You save on acetone and it's good for yield as well. Read the forum, there is plenty of posts about 4-MMC from 2b4m.
React 2b4m with methylamine. I prefer methylamine hydrochloride (easier to handle, less smell) but 40 % solution works just as well. Use whatever solvent you can get the easiest and without drawing attention, usually ethyl acetate but possibly DCM, toluene or benzene.
The process is the same: reaction, free base flushing, acidification, extraction, drying and/or recrystallization.
Consider performing acidification in aqueous environment without acetone. You save on acetone and it's good for yield as well. Read the forum, there is plenty of posts about 4-MMC from 2b4m.
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Bro there's like 20 posts with recipes about this on the forum. Read them, compare them, see the different solvents that people use and find which you can get the easiest based on your circumstances, and come back with any concrete questions that you might have. But you need to put in your own time and work first, nobody can do that for you.
Yes, all of them are feasible. Just pay attention to the details. Some videos use iodoketone while the majority of posts use bromoketone that is typically easier to source. But even then the process tends to be the same.
Try to understand the general steps, what they do and why they are included, instead of following a recipe without fundamental understanding of each step. The process of making 4-MMC from BK4 is generally reaction, free base flushing, acidification, extraction, purification. It can't get any easier once you understand the purpose of each step, why it's done and how you can adjust it to your needs.
Try to understand the general steps, what they do and why they are included, instead of following a recipe without fundamental understanding of each step. The process of making 4-MMC from BK4 is generally reaction, free base flushing, acidification, extraction, purification. It can't get any easier once you understand the purpose of each step, why it's done and how you can adjust it to your needs.