Síntesis de la mefedrona (4-MMC); fácil de realizar - alto rendimiento

[tucoXxX]

Quiero casi 1 kg de producto acabado. ¿puedo hacerlo con 3 veces la cantidad de reactivos?

 

[olduser]

mejor tomar x4 : 2Kg de bromoketona, algunas personas ni siquiera llegan al 50% de rendimiento + si lo quieres en forma cristalina, tu rendimiento disminuye

 

[w2x3f5]

no hay suficiente disolvente, 2,5 horas es demasiado y la temperatura demasiado alta, la sustancia resultó muy sucia después de añadir el ácido.

 

[SonicNL]

La hora y la temperatura son correctas. Te habrás equivocado.

 

[ghostimage]

28-32с, 1h40min, full reaction so i agree with you, i am a bulk manufacturer, make minimum of 15kgs in one turn, so this parameters cost me about a year of experiments, and you here give it to people, who just dont belive you....ahahahah what a lol ;(

 

[HerrHaber]

Hace poco conseguí un rendimiento superior al oído de clorhidrato de 4MMC en un momento en el que menos lo esperaba. Antes de hacerlo público a todo el mundo creo que son necesarias más de 5 tiradas (de 5, 2 consecutivas fueron de alto rendimiento, luego 2 pensé que las mejoraría pero no lo hice, y otra hace el triplicado necesario para que pueda afirmar esto). Sin embargo me quedé sin material y estoy deseando documentar esto completamente con fotos y todo eso. Y para no ser juzgado por retener la información "preciosa", puedo intercambiar algunos detalles contraintuitivos de la preparación:

-la agitación es clave (para mantener las capas de DCM y agua en el contacto más íntimo sin catalizador de transferencia de fase)
-el tiempo de reacción es relativamente largo (de 6 a 8 horas, suelo hacer una pausa en la agitación suponiendo que si las capas se separan, la reacción casi se detiene)
-sin aplicar calor (mi tercera y cuarta ejecución tuvieron rendimientos medios e inferiores cuando se aplicó un calentamiento suave)
-Enfriar la mezcla y los reactivos (en el paso de acidificación, los líquidos enfriados fueron los más productivos).
-filtrar rápido (justo después de que precipiten los sólidos, no dejar que se queden ya que parte del producto irá en disolución)

Espero que esto ayude y prometo volver con detalles y por que no, una validacion de otro miembro activo.

 

[mcdonalds]

hello,
i'm not sure why condenser is used in this syntessis.
is correct that is for condense methylamine gas and keep it in the reaction

 

[Naruto]

No

 

[olduser]

yes, but as methylamine is already in excess I guess it's used to reduce the smell

 

[HerrHaber]

yes, but harmful even more so

 

[William D.]

If you use cooling with liquid nitrogen, the reaction mixture in the flask would simply freeze . Therefore, only an excess that is filtered or evaporates into the atmosphere

 

[Ranbir Singh]

How can change mephedrone powder to crystel form please tell me

 

[dnBQByvHb8Zkawbjpx]

Using the process called crystallization: http://bbzzzsvqcrqtki6umym6itiixfhn...n/threads/mephedrone-4mmc-crystallization.72/

 

[agness]

Can I use a Ethyl acetate instead of Dichloromethane?

 

[olduser]

Yes

 

[lucky2222]

hello thank you for info knowledge was wonder on the sop if you had methylamine HCL instead of methylamine 40%aq what step would you use instead to make it a liquid ? thank you again for your time

 

[William D.]

@lucky2222 there is a lot of information on this forum about this. You can use water or alcohol with sodium hydroxide or triethylamine to produce gas. Triethylamine is more convenient in some cases if it is available to you.

 

[Blazey]

nice, i missed out on this chem before the bans in the uk, glad to see its around still, i wanna try it me as I love mdma

 

[lucky2222]

hello was wondering if there away to substitute methylamine 40%aq with methylamine hcl in this sop ?

 

[Rhales]

Sry I don't understand clearly your question. The addition of water is used to dissolve the polar impurities in the solution after the reaction (2B4M, methylamine, etc). You need to let it a few minutes then throw away all of the water, only the oil stays.
You can addapt the protocol to 3mmc aswell, you need to use 2-bromo-3-methylpropiophenone as main reagent and keep the same molar ratio (as they are isomers, you can keep the exact same amounts).

 

[olduser]

Sry I don't understand clearly your question. The addition of water is used to dissolve the polar impurities in the solution after the reaction (2B4M, methylamine, etc). You need to let it a few minutes then throw away all of the water, only the oil stays.
You can addapt the protocol to 3mmc aswell, you need to use 2-bromo-3-methylpropiophenone as main reagent and keep the same molar ratio (as they are isomers, you can keep the exact same amounts).

 

[Rhales]

If it's your first batch, I recommend using protocols that has been written by the forum experts. These are good too but hasn't always been tested and are more about experimentation once you already know the synth. WillD threads about mephedrone are really good

 

[olduser]

If it's your first batch, I recommend using protocols that has been written by the forum experts. These are good too but hasn't always been tested and are more about experimentation once you already know the synth. WillD threads about mephedrone are really good