Adskillelse af metamfetamin-isomerer med vinsyre

[Osmosis Vanderwaal]

@G.Patton Jeg har nogle problemer med denne proces, som jeg håber, du kan forklare mig.
Der er ingen omtale af D-meth-D-tartat eller l-meth-l-tartat. Det er de optisk aktive stereoisomerer, og jeg har ikke set noget bevis eller nogen mekanisme, der tyder på, at de ikke dannes. Da de er de optisk aktive stereoisomerer, ville de krystallisere ved en højere temperatur (dvs. tidligere) end de inaktive. Rækkefølgen ville være D,D; L,L; D,L; L,D.
Hvorfor ville det IKKE være mere omkostningseffektivt og effektivt KUN at bruge l-vinsyre, de naturligt forekommende isomerer, og fjerne ,l l-meth-krystallerne fra rm før opkoncentrering og krystallisering?

 

[G.Patton]

Dette skyldes rumlige forhindringer. De kan ikke dannes. Dette er beskrevet i litteraturen med andre eksempler på aminer. Søg efter det, hvis du er interesseret.

Det kan du, det er op til dig. Resultatet vil være det samme.

 

[EveryoneHatesCris]

Okay?

 

[Osmosis Vanderwaal]

@G.Patton I find it interesting that you are reacting ammonium chloride with sulfuric acid to make your HCL gas in this write up. I've never before heard of using that method but it is viable. Is there a reason that is preffered over the more common mixtures?

 

[G.Patton]

No difference, It's up you your local reagent availability.

 

[Osmosis Vanderwaal]

I like that there is no water to gunk up the works, like there is dehydrating HCL with H2So4. I think I'll adot this method andski the drying tube

 

[G.Patton]

It's easy to get rid of water by means of CaCl2 tube filter.

 

[Osmosis Vanderwaal]

sure, or a cold trap with H2So4 inline with the output, but if I skip that I can just have a flask, a claison adaptor with a pressure equalizing drop funnel and a hose adaptor on the side arm. 4 pieces of glass, only the drop funnel being extra from a basic distillation set

 

[prvnc]

The tartaric acid method works by selectively crystallizing d-methamphetamine as the l-tartrate salt. Control pH carefully during freebase conversion and HCl gas saturation. Hot filtration and recrystallization in ethanol boost purity but reduce yield (~30% loss normal). Always verify purity with Simon’s test. Exact tartaric acid ratios and repeat crystallizations improve results.

 

[Osmosis Vanderwaal]

theres a rule that says "a good chmist is an accurate chemist" Tartaric acid doesn't "selectively crystallise" anything. that misleading Also d-meth-l tartrate mixes more than one convention of chirality, considering
d-meth=L-Meth=R=meth=legal, and
l-meth=D-meth=S-meth=illegal