Hledal jsem na fóru a existuje mnoho různých způsobů výroby mefedronu. Jaká je podle vás syntéza, která má opravdu dobrý výtěžek, je poměrně jednoduchá a je méně pravděpodobné, že bude odhalena?
Jaká je nejlepší syntéza mefedronu (4-MMC)?
- Thread starter PabloEscobar
- Start date
Záleží na výchozích činidlech. Dobré způsoby prostřednictvím 2-bromu nebo 2-jodo-4'-methylpropiofenonu.
Hej, mohli byste říct, co dělat, když je 4methypropiophenone regulován?
- By HIGGS BOSSON
V tomto případě můžete zvolit následující možnosti:
1. Ujasnit si, zda je brom (BK-4) nebo jodoketon (IK-4) legální, a pokud je legální, objednat látku z Číny.
2. Syntetizovat 4-methylpropiofenon sami (syntéza je na fóru).
3. Nahraďte 4-methylpropiofenon ti 3-chlorpropiofenonem nebo jiným analogem.
1. Ujasnit si, zda je brom (BK-4) nebo jodoketon (IK-4) legální, a pokud je legální, objednat látku z Číny.
2. Syntetizovat 4-methylpropiofenon sami (syntéza je na fóru).
3. Nahraďte 4-methylpropiofenon ti 3-chlorpropiofenonem nebo jiným analogem.
2-Bromo-4'-methylpropiophenone (cas 1451-82-7) Making 4MMC，The simplest synthesis method?
It's not like there's too many options.
React 2b4m with methylamine. I prefer methylamine hydrochloride (easier to handle, less smell) but 40 % solution works just as well. Use whatever solvent you can get the easiest and without drawing attention, usually ethyl acetate but possibly DCM, toluene or benzene.
The process is the same: reaction, free base flushing, acidification, extraction, drying and/or recrystallization.
Consider performing acidification in aqueous environment without acetone. You save on acetone and it's good for yield as well. Read the forum, there is plenty of posts about 4-MMC from 2b4m.
React 2b4m with methylamine. I prefer methylamine hydrochloride (easier to handle, less smell) but 40 % solution works just as well. Use whatever solvent you can get the easiest and without drawing attention, usually ethyl acetate but possibly DCM, toluene or benzene.
The process is the same: reaction, free base flushing, acidification, extraction, drying and/or recrystallization.
Consider performing acidification in aqueous environment without acetone. You save on acetone and it's good for yield as well. Read the forum, there is plenty of posts about 4-MMC from 2b4m.
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Bro there's like 20 posts with recipes about this on the forum. Read them, compare them, see the different solvents that people use and find which you can get the easiest based on your circumstances, and come back with any concrete questions that you might have. But you need to put in your own time and work first, nobody can do that for you.
Yes, all of them are feasible. Just pay attention to the details. Some videos use iodoketone while the majority of posts use bromoketone that is typically easier to source. But even then the process tends to be the same.
Try to understand the general steps, what they do and why they are included, instead of following a recipe without fundamental understanding of each step. The process of making 4-MMC from BK4 is generally reaction, free base flushing, acidification, extraction, purification. It can't get any easier once you understand the purpose of each step, why it's done and how you can adjust it to your needs.
Try to understand the general steps, what they do and why they are included, instead of following a recipe without fundamental understanding of each step. The process of making 4-MMC from BK4 is generally reaction, free base flushing, acidification, extraction, purification. It can't get any easier once you understand the purpose of each step, why it's done and how you can adjust it to your needs.