I was searching the forum and there are many different ways to produce mephedrone. What do you think is the synthesis that has a really good yield, is quite simple and less likely to be detectd?
What is the best Mephedrone (4-MMC) synthesis?
- Thread starter PabloEscobar
- Start date
hey could you tell what to do if 4methypropiophenone is regulated?
- By HIGGS BOSSON
In this case, you can choose the following options:
1. Clarify whether bromo (BK-4) or iodoketone (IK-4) is legal, and if legal, order the substance from China.
2. Synthesize 4-methylpropiophenone yourself (the synthesis is on the forum)
3. Replace 4-methylpropiophenone ti 3-chloropropiophenone or another analogue
1. Clarify whether bromo (BK-4) or iodoketone (IK-4) is legal, and if legal, order the substance from China.
2. Synthesize 4-methylpropiophenone yourself (the synthesis is on the forum)
3. Replace 4-methylpropiophenone ti 3-chloropropiophenone or another analogue
2-Bromo-4'-methylpropiophenone (cas 1451-82-7) Making 4MMC，The simplest synthesis method?
It's not like there's too many options.
React 2b4m with methylamine. I prefer methylamine hydrochloride (easier to handle, less smell) but 40 % solution works just as well. Use whatever solvent you can get the easiest and without drawing attention, usually ethyl acetate but possibly DCM, toluene or benzene.
The process is the same: reaction, free base flushing, acidification, extraction, drying and/or recrystallization.
Consider performing acidification in aqueous environment without acetone. You save on acetone and it's good for yield as well. Read the forum, there is plenty of posts about 4-MMC from 2b4m.
React 2b4m with methylamine. I prefer methylamine hydrochloride (easier to handle, less smell) but 40 % solution works just as well. Use whatever solvent you can get the easiest and without drawing attention, usually ethyl acetate but possibly DCM, toluene or benzene.
The process is the same: reaction, free base flushing, acidification, extraction, drying and/or recrystallization.
Consider performing acidification in aqueous environment without acetone. You save on acetone and it's good for yield as well. Read the forum, there is plenty of posts about 4-MMC from 2b4m.
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Bro there's like 20 posts with recipes about this on the forum. Read them, compare them, see the different solvents that people use and find which you can get the easiest based on your circumstances, and come back with any concrete questions that you might have. But you need to put in your own time and work first, nobody can do that for you.
Yes, all of them are feasible. Just pay attention to the details. Some videos use iodoketone while the majority of posts use bromoketone that is typically easier to source. But even then the process tends to be the same.
Try to understand the general steps, what they do and why they are included, instead of following a recipe without fundamental understanding of each step. The process of making 4-MMC from BK4 is generally reaction, free base flushing, acidification, extraction, purification. It can't get any easier once you understand the purpose of each step, why it's done and how you can adjust it to your needs.
Try to understand the general steps, what they do and why they are included, instead of following a recipe without fundamental understanding of each step. The process of making 4-MMC from BK4 is generally reaction, free base flushing, acidification, extraction, purification. It can't get any easier once you understand the purpose of each step, why it's done and how you can adjust it to your needs.