Care este cea mai bună sinteză a mefedronei (4-MMC)?

PabloEscobar

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Am căutat pe forum și există multe modalități diferite de a produce mefedronă. Care credeți că este sinteza care are un randament foarte bun, este destul de simplă și mai puțin probabil să fie detectată?
 

G.Patton

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Depinde de reactivii de pornire. Căi bune prin 2-brormo sau 2-iodo-4'-metilpropiofenonă
 

mrreese

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hey ați putea spune ce să faceți dacă 4methypropiophenone este reglementat?
 

HIGGS BOSSON

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În acest caz, puteți alege următoarele opțiuni:
1. Clarificați dacă bromo (BK-4) sau iodocetona (IK-4) este legală, iar dacă este legală, comandați substanța din China.
2. Sintetizați singur 4-metilpropiofenona (sinteza se află pe forum)
3. Înlocuiți 4-metilpropiofenona cu 3-cloropropiofenona sau un alt analog
 

Nsowonxmd

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În cazul în care cel mai puțin. Vă uitați la.
Unde cel mai mult. Veți găsi
 

QAZ123123

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2-Bromo-4'-methylpropiophenone (cas 1451-82-7) Making 4MMC,The simplest synthesis method?
 

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It's not like there's too many options.

React 2b4m with methylamine. I prefer methylamine hydrochloride (easier to handle, less smell) but 40 % solution works just as well. Use whatever solvent you can get the easiest and without drawing attention, usually ethyl acetate but possibly DCM, toluene or benzene.

The process is the same: reaction, free base flushing, acidification, extraction, drying and/or recrystallization.

Consider performing acidification in aqueous environment without acetone. You save on acetone and it's good for yield as well. Read the forum, there is plenty of posts about 4-MMC from 2b4m.
 
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QAZ123123

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Can you give me a recipe and production process?I haven't experimented yet.I need to decide on my plan now.Then start,Thank you
 

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Bro there's like 20 posts with recipes about this on the forum. Read them, compare them, see the different solvents that people use and find which you can get the easiest based on your circumstances, and come back with any concrete questions that you might have. But you need to put in your own time and work first, nobody can do that for you.
 

QAZ123123

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Thanks for your suggestion, I will read it. Are all the methods in those videos feasible? Then I just follow the video step by step
 

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Yes, all of them are feasible. Just pay attention to the details. Some videos use iodoketone while the majority of posts use bromoketone that is typically easier to source. But even then the process tends to be the same.

Try to understand the general steps, what they do and why they are included, instead of following a recipe without fundamental understanding of each step. The process of making 4-MMC from BK4 is generally reaction, free base flushing, acidification, extraction, purification. It can't get any easier once you understand the purpose of each step, why it's done and how you can adjust it to your needs.
 
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