BENSÜÜLTSÜANİD (FENÜÜLATSETONİTRİL) AMFETAMİNSULFAADIKS.

[ossi]

tere,

kas ekspert võib ehk kirjutada sünteesi marsruuti allpool loetletud ainetega?
see sobib hästi suures mastaabis ja ma arvan, et see on huvitav paljudele siinsetele inimestele

kõik reaktiivid on odavad ja kergesti kättesaadavad

• Bensüültsüaniid (fenüülketonitriil)
• väävelhape
• pliiatsetaat trihüdraat (või muud alternatiivid)
• formamiid
• sipelghape
• HCİ
• Naatriumhüdroksiid

aitäh ette
ossi

 

[Hank Schrader]

Kõige lihtsam viis fenüülketonitriili kasutamiseks on hankida APAAN. Fenüülketonitriili peate refluksima metanoolis koos naatriummetülaadiga, pärast 6-tunnist refluksimist peate kogu metanooli ära ajama ja kogu sademe vees lahustama ning lisama jäääädikhapet jahutamise ajal. Sadestunud APAANi pestakse mitu korda veega ja kristalliseeriti ümber metanoolis. Saadud valge kristall tuleb hüdrolüüsida happes (fosfor- või soolhappes), et saada 1 liitrist fenüülketonitriilist 860 ml P2P.

Pürolüüsiprotsess, mida te niikuinii soovite teha, nõuab fenüüläädikhapet ja selle saamiseks peate niikuinii hüdrolüüsima bensüültsüaniidi.
Ma ei läheks sinu soovitud meetodiga ja kasutaks APAANi.
Kuigi meie ajal on olemas lihtsamad meetodid kui APAAN ja fenüüläädikhappesoolade pürrolüüs ...

Niipalju kui ma näen, siis sa tahad kasutada leukarti reaktsiooni amfetamiini valmistamiseks.
Reaktsioon võtab palju aega ja kui tahad teha suurt toodangut, siis mine teistmoodi.
Vt madalrõhu hüdrogeenimine metallkatalüsaatorite abil.

Leukarti abil saab toota palju toodet, kuid reaktsioon nõuab arusaamist ja palju aega.
Ja reeglina ei ületa algaja toodang pikka aega 50% molaarse massi kohta ketooni kohta.

 

[ossi]

tänan teid üksikasjaliku vastuse eest.
Probleem on selles, et see, mida te saate ise kui ilmalik õpetada, on piiratud.
riigis, kus ma praegu olen, kasutatakse neid aineid masstootmises. aga siin ei õpeta seda keegi.
otsin leuckarti meetodit suuremas mahus materjalidega, mida saab ka saada. Ma saaksin selle meetodiga hakkama.
Ma võin kergesti saada eespool mainitud materjale.
ja 50% on minu jaoks väga hea.

 

[yuiopjkl]

Ma leidsin selle

 

[Jordan Belfort]

Asendage THF nitrometaani ja metanooli 50/50% aezotroopiaga.


Kas te võtate sobiva lahusti, THF-i või nitrometaani (kuid peate kontrollima, kas see ei ole raskesti metüülamiini tekitav), ja lisate magneesiumilaastud ning lasete neil reageerida joodometaaniga, kuni magneesiumilaastud täielikult lahustuvad.
See on ainult teie metüülmagneesiumjodiidi valmistamiseks.

Nüüd on teil 1 pot sünteesida metamfetamiini ilma metüülamiini ja saate destilleerida kõik lahustid ja taaskasutada.

Tehes seda onepot nagu Hg/Al Ga/Al on tõenäoliselt liiga eksotermiline ja teeb kuradi jama. Soovitan aeglaselt ketooni peale tilkuda.

Ma pean ütlema, et see suhe töötab BMK jaoks ultraheli abil.

 

[Jordan Belfort]

Oh te võite tõsta grignardi pH-d puhta naatriumhappegaasi abil 8-9-ni.

 

[caesare.robot]

Q on samuti huvitatud, kui keegi on selle meetodi kohta positiivset vastust ...

 

[yuiopjkl]

Ma ei ole seda proovinud.
Küsige ekspertidelt. Neil võib olla teadmisi ja nõuandeid

@G.Patton @HIGGS BOSSON

 

[ossi]

ja palun, kas keegi saab skaalata 1000gr?
@G.Patton @William Dampier @HEISENBERG

 

[G.Patton]

Kirjutasin moolide, grammide, liitrite ja keemiliste arvutuste teema spetsiaalselt selliste küsimuste jaoks
=> Kuidas lugeda reaktiive?

 

[Hank Schrader]

See on kasutu süntees. Grignardi reaktiiv, suures koguses lahusteid. See on kui ainult teaduslik huvi, siis saab seda teha 1 kord enam mitte. Kommertssünteesi jaoks ei ole mingit väärtust.

Võttes bensüültsüaniidi, on väga lihtne saada fenüüläädikhapet, ja tööstuslikus mastaabis teha pürrolüüsi soolade, saagis ei ole kõrgeim, kuid väga mugav. Lõpptoode on kolme ketooni segu, mida on lihtne fraktsioneerida.

 

[Jordan Belfort]

Grignardi reaktiivid on tegelikult head. Eriti kui lisada ka tsinkkloriidi.

Kui te kasutate ultraheli, ei ole teil vaja veevaba reaktiivi.

 

[ossi]

ma oleksin ääretult tänulik, kui te kirjutaksite mulle sünteesi nende reagentidega. aga amatöörile
40%-50% saagis on ok @Hank Schrader

 

[ossi]

Vabandust, ma vist jätsin selle kahe silma vahele, kuigi ma loen siin palju

 

[FQ-BB]

List of reagents

- Use 12.65 kg of benzyl cyanide.
- Require 20 liters of concentrated sulfuric acid (H₂SO₄, 96%).
- Prepare 30 liters of deionized water.
- Use 18 liters of formamide.
- Require 12 liters of formic acid (HCOOH, 99%).
- Prepare 5 kg of sodium carbonate (Na₂CO₃).
- Use 5 liters of hydrochloric acid (HCl, 37%).
- Require 2 kg of sodium hydroxide (NaOH).
- Use 50 liters of dichloromethane (CH₂Cl₂).
- Optionally use 2 kg of lead acetate trihydrate (Pb(C₂H₃O₂)₂·3H₂O).

List of utensils and tools

- Use a 50-100 liter stainless steel or glass-lined reactor with a mechanical stirrer and equipped with temperature control (±2°C).
- Equip an industrial-grade condenser with a cooling circulation system.
- Equip an industrial-grade liquid separation device with a capacity of ≥10 liters.
- Install a large distillation tower with a condensing device and a collecting device with a capacity of ≥20 liters.
- Use an industrial Buchner funnel or filter press for solid-liquid separation.
- Prepare a corrosion-resistant storage tank with a capacity of ≥50 liters.
- Prepare a measuring cylinder (2 liters, 10 liters) and a beaker (500 ml to 5 liters).
- Use an industrial stirring device to ensure uniform mixing.
- Prepare a vacuum pump for vacuum distillation.
- Ensure that there are explosion-proof equipment, ventilation systems and fire extinguishers.
- Provide protective equipment such as protective gloves, goggles, gas masks and acid-proof aprons.

Step 1: Hydrolysis of benzyl cyanide to produce acetophenone

- Add 12.65 kg of benzyl cyanide and 30 liters of deionized water to the reactor, and start the agitator to make the solution uniform.
- Slowly add 20 liters of concentrated sulfuric acid in batches, and control the reaction temperature at 30-50°C to prevent violent exotherm.
- Heat the reaction mixture to 150°C for 1-2 hours and observe the color change from transparent to light brown.
- After cooling to room temperature, separate the acetophenone organic layer with a separatory funnel.
- Collect the 202°C fraction by distillation to obtain purified acetophenone.

Step 2: Acetophenone generates N-methylphenylethylamine through Leuckart reaction

- Add 13.05 kg of acetophenone and 18 liters of formamide to the reactor and start the agitator to mix evenly.
- Slowly add 12 liters of formic acid to ensure that the reactants are fully mixed.
- Heat to 120-140°C and maintain for 3-5 hours. The released gas is discharged through the condenser.
- After the reaction is completed, cool to room temperature and neutralize the mixture in a saturated solution of about 5 kg of sodium carbonate.
- Extract the reaction solution with 50 liters of dichloromethane in 5 times, dry and distill, collect the 194°C fraction, and obtain purified N-methylphenylethylamine.

Step 3: Post-treatment and purification

- Dissolve the purified N-methylphenylethylamine in a small amount of water and acidify to pH about 1 with 5 liters of hydrochloric acid to form the hydrochloride.
- If there are impurities, add 2 kg of lead acetate trihydrate, stir and filter the precipitate.
- Release the free N-methylphenylethylamine with 2 kg of sodium hydroxide solution, then extract it again with dichloromethane, dry and distill.

I reiterate that I am only a hobbyist and do not sell any precursors or substances. Anyone violating escrow transactions is a scammer.

Respect to BB administrators. Salute 🫡

 

[G.Patton]

Kirjutasin selle paar päeva tagasi.

 

[FQ-BB]

Is there a reward?

 

[FQ-BB]

I'll challenge

 

[FQ-BB]

List of reagents

- Use 12.65 kg of benzyl cyanide.
- Require 20 liters of concentrated sulfuric acid (H₂SO₄, 96%).
- Prepare 30 liters of deionized water.
- Use 18 liters of formamide.
- Require 12 liters of formic acid (HCOOH, 99%).
- Prepare 5 kg of sodium carbonate (Na₂CO₃).
- Use 5 liters of hydrochloric acid (HCl, 37%).
- Require 2 kg of sodium hydroxide (NaOH).
- Use 50 liters of dichloromethane (CH₂Cl₂).
- Optionally use 2 kg of lead acetate trihydrate (Pb(C₂H₃O₂)₂·3H₂O).

List of utensils and tools

- Use a 50-100 liter stainless steel or glass-lined reactor with a mechanical stirrer and equipped with temperature control (±2°C).
- Equip an industrial-grade condenser with a cooling circulation system.
- Equip an industrial-grade liquid separation device with a capacity of ≥10 liters.
- Install a large distillation tower with a condensing device and a collecting device with a capacity of ≥20 liters.
- Use an industrial Buchner funnel or filter press for solid-liquid separation.
- Prepare a corrosion-resistant storage tank with a capacity of ≥50 liters.
- Prepare a measuring cylinder (2 liters, 10 liters) and a beaker (500 ml to 5 liters).
- Use an industrial stirring device to ensure uniform mixing.
- Prepare a vacuum pump for vacuum distillation.
- Ensure that there are explosion-proof equipment, ventilation systems and fire extinguishers.
- Provide protective equipment such as protective gloves, goggles, gas masks and acid-proof aprons.

Step 1: Hydrolysis of benzyl cyanide to produce acetophenone

- Add 12.65 kg of benzyl cyanide and 30 liters of deionized water to the reactor, and start the agitator to make the solution uniform.
- Slowly add 20 liters of concentrated sulfuric acid in batches, and control the reaction temperature at 30-50°C to prevent violent exotherm.
- Heat the reaction mixture to 150°C for 1-2 hours and observe the color change from transparent to light brown.
- After cooling to room temperature, separate the acetophenone organic layer with a separatory funnel.
- Collect the 202°C fraction by distillation to obtain purified acetophenone.

Step 2: Acetophenone generates N-methylphenylethylamine through Leuckart reaction

- Add 13.05 kg of acetophenone and 18 liters of formamide to the reactor and start the agitator to mix evenly.
- Slowly add 12 liters of formic acid to ensure that the reactants are fully mixed.
- Heat to 120-140°C and maintain for 3-5 hours. The released gas is discharged through the condenser.
- After the reaction is completed, cool to room temperature and neutralize the mixture in a saturated solution of about 5 kg of sodium carbonate.
- Extract the reaction solution with 50 liters of dichloromethane in 5 times, dry and distill, collect the 194°C fraction, and obtain purified N-methylphenylethylamine.

Step 3: Post-treatment and purification

- Dissolve the purified N-methylphenylethylamine in a small amount of water and acidify to pH about 1 with 5 liters of hydrochloric acid to form the hydrochloride.
- If there are impurities, add 2 kg of lead acetate trihydrate, stir and filter the precipitate.
- Release the free N-methylphenylethylamine with 2 kg of sodium hydroxide solution, then extract it again with dichloromethane, dry and distill.

I reiterate that I am only a hobbyist and do not sell any precursors or substances. Anyone violating escrow transactions is a scammer.

Respect to BB administrators. Salute 🫡

 

[tin ton]

* Benzylacetone → Hydrazine (NH₂NH₂) Condensation → Strong Alkali Reduction → P2P

Steps:
Benzylacetone (10 g) anhydrous hydrazine (NH₂NH₂·H₂O, 98%) 15 m potassium hydroxide (KOH) 10 g ethylene glycol (solvent) 50 mL
- In a flask, add benzylacetone and anhydrous hydrazine, reflux and stir for 3 hours.Add KOH, heat up to 180°C and continue heating for 2 hours (Wolff-Kishner reduction). Cool down, extract, and distill (202-205°C) to collect P2P.Key point: Wolff-Kishner requires high temperature (180°C), avoid rapid heating.

 

[FQ-BB]

* Benzylacetone → Hydrazine (NH₂NH₂) Condensation → Strong Alkali Reduction → P2P

Steps:
Benzylacetone (10 g) anhydrous hydrazine (NH₂NH₂·H₂O, 98%) 15 m potassium hydroxide (KOH) 10 g ethylene glycol (solvent) 50 mL
- In a flask, add benzylacetone and anhydrous hydrazine, reflux and stir for 3 hours.Add KOH, heat up to 180°C and continue heating for 2 hours (Wolff-Kishner reduction). Cool down, extract, and distill (202-205°C) to collect P2P.Key point: Wolff-Kishner requires high temperature (180°C), avoid rapid heating.